RNA: a possible contributor to the 'missing heritability’
نویسندگان
چکیده
منابع مشابه
RNA: a possible contributor to the 'missing heritability’
A number of human pathologies have a transmission pattern that does not obey Mendelian segregation rules. This type of heredity is defined as non-Mendelian and is based on mechanisms of transgenerational epigenetic inheritance. Comprehensive information on the molecular mechanisms of it is still lacking. However, recent evidence from distantly related species including Caenorhabditis elegans, D...
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Human genetics has been haunted by the mystery of "missing heritability" of common traits. Although studies have discovered >1,200 variants associated with common diseases and traits, these variants typically appear to explain only a minority of the heritability. The proportion of heritability explained by a set of variants is the ratio of (i) the heritability due to these variants (numerator),...
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ژورنال
عنوان ژورنال: Basic and Clinical Andrology
سال: 2013
ISSN: 2051-4190
DOI: 10.1186/2051-4190-23-9